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A Hospital-University Federation (FHU) is a center of excellence that brings together hospital teams, universities and research units around a leading-edge medical or scientific theme, in close collaboration with national research organizations and industrial partners.
FHUs are a key pillar of AP-HP’s strategy for research, education and innovation, developed in partnership with Inserm and Universities.
Context and Challenges
In an increasingly competitive international environment, marked by the emergence of new health, technological and societal challenges, strengthening translational and clinical research is essential.
The creation of Hospital-University Federations by AP-HP, Inserm and universities aims to strengthen links between hospitals, universities and research units, structure ecosystems of excellence and accelerate the transfer of innovation for the direct benefit of patients.
Objectives of the FHU, spearheads of AP-HP
FHUs aim to promote ambitious collaborative projects bringing together hospitals, universities, research units and institutional and industrial partners.
For the 2025–2030 period, 26 Hospital-University Federations have been accredited for a five-year term.
All University Hospital Federations (FHU) : 26 FHUs in total
Coordinator
Project Manager
Location
Website
Keywords
FHU CARE2
Cancer and Autoimmune / Inflammatory diseases Relationships – 2
Samuel Jean Bitoun, Camille Bigenwald, Xavier Mariette
Myriam Morcel
Hôpital Bicêtre AP-HP, Université Paris-Saclay, Inserm U1184, Gustave Roussy
Cancer I Autoimmune diseases I T cell engager bispecific antibodies I CAR-T cells I Immune Checkpoints ICI
FHU BREATH
Bridging Research Efforts Against The Hush of Dyspnea
Laure Serresse
Narimane Zeghbib
Hôpital de la Pitié Salpêtrière AP-HP, Sorbonne Université, Inserm UMR-S 1158
Dyspnoea suffering I Invisible suffering I Interdisciplinarity I Collaboration – Innovation
FHU COMET
Complement expertise and Therapeutics : from prototypical diseases to public health Issues
Sophie Chauvet, Marie Agnès Dragon Durey
Julia Roquigny
Hôpital Européen Georges-Pompidou AP-HP, U1138 Université Paris Cité – Inserm
Coming soon
Coming soon
FHU COURNAND
Transforming Pulmonary Vascular Medicine (André Cournand : prix Nobel de physiologie ou médecine en 1956)
David Montani, Marc Humbert
Coming soon
Hôpital Bicêtre AP-HP, Université Paris Saclay, Inserm U999
Dyspnoea suffering I Invisible suffering I Interdisciplinarity I Collaboration I Innovation
FHU FOR LIFE
FédératiOn de Recherche pour la mise en Lumière par l’Imagerie du fœtus
Laurent Salomon, David Grevent
Iris Arsenakis
Hôpital Necker-Enfants malades, AP-HP, LUMIERE, URP 7328 FETUS, Université Paris Cité
Fœtus | IRM | Diagnostic prénatal | Cœur fœtal | Cerveau fœtal | Placenta | Chirurgie fœtale in utero | Data
FHU FRAME
Finding Answers to Manage Endometriosis
Louis Marcellin
Rime Lihi
Hôpital Cochin AP-HP, U1016 Université Paris Cité – Inserm
Coming soon
Endometriosis I Adenomyosis I Pain I Fertility
FHU GIFT
GroupE–Île-de-France Transplantation
Camen Lefaucheur, Filomena Conti, Claire Goumard, Jérôme Le Pavec
Amina Malek
Néphro/Tx rénale HSL (UPC) – Hépatol. Pitié‑Salp. AP‑HP/SU – Pneumo H. Marie‑Lannelongue GHSJ (UPSaclay)
Coming soon
Transplantation I Regeneration, Immunosuppression I Transversality
FHU GLIMMER
Gut, Liver and Microbiome Research
Harry Sokol, Dominique Thabut
Mina Ahloulay
Hôpital Saint-Antoine AP-HP, Sorbonne Université, Inserm U938, CRSA
IBD I Microbiome I Liver I Cancer I Nutrition
FHU IMPEC
IMProving Emergency Care
Yonathan Freund
Vanessa Lemaitre
Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Université, UMRS 1166
Emergency I Research Care
FHU INDIRA
Improving Survival in Immunocompromised Patients with of Acute Respiratory Failure
Elie Azoulay
Igor Théodose
Hôpital Saint-Louis AP-HP, U1342 Université Paris Cité – Inserm
Intensive care I respiratory distress I immunocompromised patients
FHU INFIRE
INnovation Fibrosis Inflammation REmodeling
Raphael Borie, Camille Cohen, Grégory Ducrocq
Djamila Ouaret
Hôpital Bichat AP-HP, Université Paris Cité, Inserm U1149 Université Paris Cité – Inserm
Fibrosis I Inflammation I Tissue remodeling
FHU INFLAMME
Deciphering and treating undefined inflammation by precision medicine
Sophie Georgin-Lavialle
Zohra Aknouche
Hôpital Tenon AP-HP, Sorbonne Université, Inserm U1155
https://www.fhu-inflamme.fr
Inflammation I Genomics I Precision diagnostics
FHU MAMUTH
Musculoskeletal Diseases and Therapeutic Innovations
Raphaël Vialle, Denis Furling
Nezha Lenzi
Hôpital Trousseau AP‑HP, Sorbonne Université, Inserm U974
Neuromuscular Diseases I Musculoskeletal Diseases I Spinal Diseases, Innovative Therapies I Biotherapies
FHU MOSAIC²
Multiscale Optimized Strategy for Artificial Intelligence-based Imaging Biomarkers in Cancers
Valérie Paradis
Gabriel Cordova
Hôpital Beaujon AP-HP, U1149 Université Paris Cité – Inserm
Imagomics I AI I Cancer
FHU NeuroVasc 2030
Removing technological, regulatory and safety barriers to the use of innovative digital approaches to significantly improve stroke care and research
Eric Jouvent, Vincent Doat-Sarfati
Estelle Dubus
Hôpital Lariboisière AP-HP, U1141 Université Paris Cité – Inserm
Stroke, Artificial Intelligence, Innovation
FHU Prem’IMPACT
PREMaturity and its consequences: IMproving Prevention And Care Through innovation
Olivier Baud
Laurence Raclet
Hôpital Cochin AP-HP, U1153, U1141 Université Paris Cité – Inserm
Prematurity I Perinatal inflammation I Complicated Pregnancies
FHU PREVENT-HT
Predict and prevent heart failure in young subjects
Karim Wahbi
Yacine Mazouzi
Hôpital Cochin AP-HP, Université Paris Cité U970, laboratoire associé Imagine Paris Cardiomyopathy Center
Heart Failure I Genomics I Cardiomyopathy
FHU PROTHEE-2
PROsTHEtic joint infections (PJI): integrative study of immunoresponse, dynamics of bone loss and microbiological Environment in a challenging infection to develop innovative strategies of PReventiOn, THErapy and resEarch
David Lebeaux
Emilie Lereclus
Hôpital Lariboisière AP-HP, Service de Maladies Infectieuses et Tropicales
Prosthesis I infection I Bone
FHU RedGene
Gene Therapy in Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease
Sébastien Maury
Gaëlle Sandillon
Hôpital Henri-Mondor AP-HP, Université Paris Est Créteil Val de Marne, Inserm U955
Sickle Cell Disease I Thalassemia I Gene Therapy
FHU S2C-HOPE
Safety and Security of Care in Hematology and Oncology Programs of Excellence
Mohamad Mohty
Sabrina Leclercq
Hôpital Saint-Antoine AP-HP, Sorbonne Université, Inserm U938
Safety I Prevention I Cancer I Toxicities
FHU SENCODE
Targeting cellular senescence to repair the regeneration process in age-related diseases
Laurent Boyer, Jean-Yves Thuret
Anne Boiret
Hôpital Henri‑Mondor, AP‑HP, Université Paris‑Est Créteil , Inserm U955, CEA Saclay, Institut Joliot
Senescence, I Regeneration
FHU TRANSVIR
Innovative strategies to treat chronic viral infections after hematopoietic stem cell and solid organ transplantation
Jérôme Le Goff
Lina Noirot
Hôpital Saint-Louis AP-HP, UMR 722/U944, Université Paris Cité
Transplantation I Virology I Immunotherapies
FHU Treat-FND
Improving Diagnosis, Treatment and Research in a frequent and overlooked disease: the Functional Neurological Disorders
Béatrice Garcin
Angéline Maillard
Hôpital Avicenne AP-HP, Université Sorbonne Paris Nord, Inserm U1127
Coming soon
Functional neurological disorders I Treatment I Diagnosis, physiopathology
FHU TSUNAMI
Towards Strategies for Unmet Needs in Acute Mesenteric Ischemia
Alexandre Nuzzo, Olivier Corcos
Déborah François
Hôpital Beaujon AP-HP, U1148 Université Paris Cité – Inserm
Mesenteric ischemia,I Biomarker, I Diagnosis
FHU UMANHYS
Upgrading the MANagement of chronic HYpoventilation through Sleep
Maxime Patout, Antoine Léotard
Ghislain N’dah-Sekou
Hôpital Pitié-Salpêtrière, Sorbonne Université, Inserm U1158, hôpital Raymond-Poincaré, Université Paris Saclay, Inserm U1179
Coming soon
Hypoventilation I Respiratory failure I Sleep
FHU VEAVE
Violence against children and adolescents and their lifelong consequences
Martin Chalumeau
Olivia Rousset Torrente
Hôpital Necker-Enfants malades AP-HP, U1153 Université Paris Cité – Inserm
Child abuse and neglect I Epidemiology I Neuroscience